The Regiment was authorized on April 13, 1776 in the North Carolina State Troops as the 6th North Carolina Regiment. Adopted on May 7, 1776 into the Continental Army and assigned to the Southern Department. Relieved on February 5, 1777 from the Southern Department and assigned to the Main Continental Army. It was assigned on July 8, 1777 to the North Carolina Brigade, an element of the Main Continental Army. Reorganized in fall 1778 at Halifax to consist of 9 companies. It was assigned on January 11, 1779 to Sumner's Brigade, an element of the Southern Department. Disbanded on January 1, 1781.