The Tyrrell County Regiment was one of the 35 existing county militias to be authorized as a regiment of the North Carolina militia by the North Carolina Provincial Congress on September 9, 1775. It was active until the end of the war. The Tyrrell County Regiment was engaged in the Battle of Brier Creek in Georgia on March 3, 1779, the Siege of Charleston from March 28 to May 12, 1780, and the Battle of Eutaw Springs in South Carolina on September 8, 1781.