The Regiment was authorized on November 13, 1775 in the South Carolina State Troops as the 4th South Carolina Regiment. Organized between November 20- December 18, 1775 at Charleston to consist of three companies from the greater Charleston area. Adopted on June 18, 1776 into the Continental Army and assigned to the Southern Department. Expanded on October 18, 1776 to consist of six companies. Captured on May 12, 1780 at Charleston by the British Army. Disbanded on January 1, 1781.